We offer a wide range of key antibodies to research and diseases related to bone and calcium metabolism, including Parathyroid Hormone (PTH), Calcitonin, Osteocalcin.
Parathyroid hormone (PTH), also known as parathormone or parathyroid, is secreted by the parathyroid glands. PTH acts to increase the release of calcium from the bones and increase blood Ca2 + levels, while calcitonin (a hormone produced by the thyroid gland) counteracts PTH to lower calcium concentration.
Unbalanced PTH levels are associated with diseases such as hyperparathyroidism, hypoparathyroidism, familial hypocalciuric hypercalcemia, and osteoporosis.
Osteocalcin (BGLAP) is secreted by osteoblasts and plays a role in bone mineralization and calcium ion homeostasis. It is often used as a bioindicator to monitor bone formation during the treatment of osteoporosis. Research has also suggested that osteocalcin may be linked to male fertility as it may improve testosterone synthesis. We also offer vitamin D analysis which is an unavoidable link and inform us about bone metabolism.